Relationship between drug diffusion pattern after lower thoracic paravertebral block and levels of sensory nerve blockade, postoperative analgesia

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100050020

Enrollment

Unknown

Registered

2021-08-16

Start date

2021-09-01

Completion date

Unknown

Last updated

2022-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

regional block

Interventions

low thoracic paravertebral block group:ultrasound-guidedthoracic paravertebral block

Eligibility

Sex/Gender

All

Age

20 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. ASA I-III; 2. 20-70 years old patients; 3. Patients undergoing laporascopic nephrectomy under general anesthesia; 3. Patients with BMI less than 26kg / m2; 4. Subjects with normal liver and kidney functions; 5. Patients were aware of the study and signed informed consent.

Exclusion criteria

Exclusion criteria: 1 Puncture site infection; 2 Anticoagulation status; 3 Allergy to local anesthetics; 4. Serious cardiovascular disease, blood disease; 5. Alcohol abuse; 6. Combined with myasthenia gravis or Parkinson's disease or pregnancy status; 7. History of previous spinal surgery; 8. Cognitive dysfunction before surgery, unable to cooperate with pain assessment.

Design outcomes

Primary

Measure	Time frame
drug diffusion pattern 10 minutes after block;levels of sensory nerve blockade 10 minutes after block;Visual Analog VAS Score;	—

Secondary

Measure	Time frame
PCA amount;incidence of adverse reactions ;	—

Countries

China

Contacts

Public ContactWang Yun

Beijing Chaoyang Hospital, Capital Medical University

wangyun129@ccmu.edu.cn+86 10 13521611825

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026