Kidney Disease
Conditions
Interventions
Gold Standard:Pathological examination
Sponsors
Department of Urology, Renji Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Case group (histologically confirmed chromophobe carcinoma): 1. Aged >=18 years old; 2. Before undergoing routine partial nephrectomy or radical resection, provide 10mL blood samples before treatment and tissue samples after surgical resection, and store them in the biological sample bank; 3. Diagnosed with renal chromophobe carcinoma after surgery; Interference group (histologically confirmed oncocytic adenoma): 1. Age >=18 years old, gender is not limited; 2. Before receiving conventional partial nephrectomy or radical operation, provide 10mL blood samples before treatment and tissue samples after surgical resection, and store them in the biological sample bank; 3. Diagnosed with renal oncocytoma after surgery; Healthy control group: 1. Age >=18 years old, gender is not limited; 2. 10mL blood samples can be provided during physical examination and stored in the biological sample bank; 3. People with normal imaging examination results and no suspected tumors of other organs.
Exclusion criteria
Exclusion criteria: 1. Patients with any active autoimmune disease or known history of autoimmune disease (type 1 diabetes mellitus, residual hypothyroidism due to autoimmune disease requiring hormone replacement, psoriasis not requiring systemic therapy or in the absence of external cases where no recurrence is expected in the presence of triggering factors, however, are eligible to participate in this trial); 2. Patients with adrenal insufficiency; 3. Known HIV or known AIDS-positive patients; 4. Positive hepatitis B virus surface antigen or hepatitis C virus RNA test indicates active or chronic infection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood routine;creatinine clearance; | — |
Countries
China
Contacts
Public ContactZhai Wei
Shanghai Jiaotong University School of Medicine, Renji Hospital
Outcome results
None listed