Rectal cancer
Conditions
Interventions
Stent-based Diverting Technique Group:Stent-based Diverting Technique
Prophylactic ileostomy group:Prophylactic ileostomy
Sponsors
Run Run Shaw Hospital Affiliated to Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Primary solitary rectal cancer confirmed pathologically; 2.Patients receive low anterior resection; 3.Age from over 18 to under 80 years; 4.ECOG(Eastern Cooperative Oncology Group)<=1; 5.ASA(American Society of Anesthesiology) grade <=III; 6.Nutrition score (NRS)<=2; 7.Written informed consent.
Exclusion criteria
Exclusion criteria: 1. Previous rectal surgery; 2. Familial colorectal polyposis, hereditary non-polyposis colorectal cancer, active Crohn's disease or active ulcerative colitis; 3. Cardio-cerebrovascular disease, unstable angina pectoris, acute myocardial infarction within six months; 4. Continue to use glucocorticoids within one month; 5. Pregnant or planning pregnancy and lactating women; 6. Severe mental disorder; 7. Other adjuvant therapy before surgery: targeted/immunotherapy; 8. Serious complications cannot tolerate surgery or require emergency surgery; 9. Intraoperative discovery of multiple rectal tumors or distant metastasis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severe complications within post-operative 90 days; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total complications within post-operative 90 days;The incidence of coloanal or colorectal anastomosis within post-operative 90 days ;Post-operative hostipal stay and cost ;Quality of life assessment at post-operative 90-day ;Changes in intestinal flora before operation and at post-operative 90-day ; | — |
Countries
China
Contacts
Public ContactCai Xiujun
Run Run Shaw Hospital Affiliated to Zhejiang University School of Medicine
Outcome results
None listed