Myocardial injury after noncardiac surgery
Conditions
Interventions
Dexmedetomidine group:Dexmedetomidine
Control Group:Normal saline
Sponsors
the First Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: Aged >= 65 years old, ASA status I-III, undergoing elective major noncardiac surgery under general anesthesia (gastrointestinal, hepatobiliary-pancreatic, thoracic, gynecologic, urologic, orthopedic).
Exclusion criteria
Exclusion criteria: Sick sinus syndrome, severe bradycardia (heart rate < 50 beats/min), left ventricular ejection fraction < 30% or heart failure, second-degree or greater atrioventricular block without pacemaker, expected length of postoperative hospital stay < 72 hours, or refusal to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of myocardial injury after noncardiac surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Myocardiac ischemic symptoms;Major Adverse Cardiovascular Event Rates;The incidence of myocardial infarction;The incidence of heart block;The incidence of cardiac arrest;The incidence of stroke;The incidence of coma;Length of ICU stay;Length of postoperative hospital stay;Sepsis;Pneumonia;Liver dysfunction;Renal dysfunction;30-day all-cause mortality; | — |
Countries
China
Contacts
Public ContactJi Fuhai
the First Affiliated Hospital of Soochow University
Outcome results
None listed