Mild Cognitive Impairment
Conditions
Interventions
Sponsors
Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Meet the MCI diagnostic criteria; 2. Aged 65-85 years old; 3. Han nationality, right-handed; 4. MoCA-B score: years of education 12 years, score <= 24; 5. Agree to sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Dementia; 2. Nervous system diseases: cerebrovascular disease, encephalitis, brain tumor, brain trauma, epilepsy, Parkinson's disease and other neurological diseases that cause cognitive decline; 3. Metabolic diseases: Anemia, abnormal thyroid function, folic acid and vitamin B12 deficiency, etc. lead to cognitive decline; 4. Severe mental illness, such as severe depression; 5. History of gas poisoning; 6. History of general anesthesia; 7. Suffering from acute or serious life-threatening diseases; 8. Severe vision, hearing or language problems cannot complete neuropsychological assessment; 9. Taking psychotropic drugs or drug abuse; 10. There are contraindications for MRI (pacemaker, metal joints).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal cognitive assessment-basic, MoCA-B; | — |
Secondary
| Measure | Time frame |
|---|---|
| auditory verbal learning test,AVLT;Shape Wiring Quiz A and B;animal word fluency;Boston naming test; | — |
Countries
China
Contacts
Public ContactFang Jiliang
Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Outcome results
None listed