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Effect of donor characteristics on T cell replete haploidentical stem cell transplantation

Effect of donor characteristics on T cell replete haploidentical stem cell transplantation

Status
Recruiting
Phases
Phase 2
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100049939
Enrollment
Unknown
Registered
2021-08-14
Start date
2021-08-10
Completion date
Unknown
Last updated
2022-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hematological malignacies

Interventions

treatment group:none

Sponsors

The First Affiliated Hospital of Medical College of Zhejiang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. The subjects or their legal representatives signed the informed consent form before the start of the clinical study; 2. Men and women are not limited, and women of childbearing age have a negative pregnancy test within 14 days before starting the test drug; 3. Age 15-67 years old; 4. Patients with malignant hematological diseases who received in vivo non-T-depleted allogeneic haploidentical hematopoietic stem cell transplantation derived from peripheral blood stem cells; 5. ECOG physical fitness score 0~2 points; 6. No major organ dysfunction.

Exclusion criteria

Exclusion criteria: 1. Combined with active infection; 2. Patients diagnosed with aplastic anemia before transplantation or patients who died within 2 months after transplantation; 3. Combined with secondary tumor; 4. Severe central nervous system disease or mental illness makes it impossible to choose to enter or withdraw from clinical trials.

Design outcomes

Primary

MeasureTime frame
Overall Survival;

Secondary

MeasureTime frame
Non-relapse mortality;Cumulative incidence of graft versus host disease;disease free survival;

Countries

China

Contacts

Public ContactHuang He

The First Affiliated Hospital of Medical College of Zhejiang University

hehuangyu@126.com+86 13605714822

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026