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Effectiveness and safety of intraspinal or introvenous steroid administration after lumbar surgery

Effectiveness and safety of intraspinal or introvenous steroid administration after lumbar surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100049935
Enrollment
Unknown
Registered
2021-08-14
Start date
2021-08-10
Completion date
Unknown
Last updated
2022-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar disc herniation

Interventions

group A:Topical epidural steroid administration
group B:Intravenous use of steroid hormones

Sponsors

The First Medical Center of the Chinese People's Liberation Army General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 18-65 who are planning to undergo lumbar fusion surgery; 2. ASA I~III; 3. BMI <32; 4. The patient is skeletal mature, with stable health according to physical examination and medical history, able to perform surgery and participate in subsequent experimental projects, and able to comply with follow-up.

Exclusion criteria

Exclusion criteria: 1. Patients with diseases that may affect nerve tissue; 2. Patients who have undergone back surgery; 3. Patients with open dura mater; 4. Acute or chronic, local or systemic infection (including a history of infection) or sepsis, with active infection foci in the spine or other parts of the body; 5. Patients with mental illness or patients are mentally incapable or unable to understand the requirements of participating in research; 6. The subject is immunosuppressed, suffering from autoimmune disease or immunosuppressive disorder; 7. Patients with adrenal cortical dysfunction (Cushing, etc.); 8. Pregnant and lactating women; 9. Long-term alcoholism, drug abuse and other patients.

Design outcomes

Primary

MeasureTime frame
pain visual analogue scale;

Countries

China

Contacts

Public ContactFeng Zeguo

The First Medical Center of the Chinese People's Liberation Army General Hospital

beijing_301@sina.com+86 13901118757

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026