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Study on instant effects of acupuncture on cerebral hemoglobin of patients with post-stroke depression and its mechanism:functional near-infrared spectroscopy

Study on instant effects of acupuncture on cerebral hemoglobin of patients with post-stroke depression and its mechanism:functional near-infrared spectroscopy

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100049921
Enrollment
Unknown
Registered
2021-08-11
Start date
2020-07-05
Completion date
Unknown
Last updated
2022-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post-stroke depression

Interventions

Sponsors

The People's Hospital of Suzhou New District
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 80 Years

Inclusion criteria

Inclusion criteria: It referred to the Key Points for Diagnosis of Various Cerebrovascular Diseases approved by the 4th National Academic Conference of Cerebrovascular Diseases of the Chinese Medical Association in 1995. All cases were confirmed by head CT or MRI, and conformed to the diagnosis of organic depression specified in the Chinese Classification and Diagnostic Criteria of Mental Disorder (3rd Edition, CCMD-3). The degree of depression was evaluated using the HAMD-17: 7-17 points indicate mild depression, while 18-24 points and > 24 points indicate moderate and severe depression respectively. 1. those meet the above diagnostic criteria; 2. aged 30-80 years old; 3. motor function deficit of at least one limb; 4. clear consciousness, no aphasia or severe intellectual damage; 5. no history of severe heart, liver and kidney diseases, epilepsy, glaucoma or mental illness; 6. The diagnosis of all cases was completed by physicians with senior professional titles in the departments of neurology and psychology; 7. those who have signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. those with a history of other mental diseases before the onset; 2. those with conscious disturbance, aphasia and dementia after the onset; 3. those with a history of long-term alcohol and drug abuse, and drug dependence; 4. those with obvious liver and renal dysfunction according to the laboratory examination; 5. those with neurological or musculoskeletal diseases that affect the recovery of functions before the onset.

Design outcomes

Primary

MeasureTime frame
peak/average value of oxygenated hemoglobin concentration during the task stage (peak oxy-Hb (mMmm)/averaged oxy-Hb (mMmm));nitial activation speed of oxygenated hemoglobin during the task stage (K-activation);the integral value of the activation response of oxygenated hemoglobin during the task stage (S-integration);the reaction time when the integral value of the oxygenated hemoglobin reaches half of that in the whole process (T-center);

Countries

China

Contacts

Public ContactXiaoman Liu

The People's Hospital of Suzhou New District

790587457@qq.com+86 0512 69585180

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026