port-wine stains
Conditions
Interventions
Sponsors
Shanghai Ninth People's Hospital, Shanghai Jiaotong University School Of Medicine
Eligibility
Sex/Gender
All
Age
1 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged over 1 year old; 2. The diagnosis of port-wine stain is clear; 3. Simple PWS and related syndromes including SW syndrome (Sturge-Weber syndrome, SWS), phakomatosis pigmentovascularis (PPV), etc. can be included, requiring erythema and syndrome Other lesions are relatively isolated, that is, there are no other related skin pathological changes in the erythema, such as dermal melanocytosis, etc.; 4. Never received photodynamic therapy in the erythema area before; 5. The time interval between photodynamic therapy and the last pulsed dye laser treatment is at least 3 months; 6. After fully understanding the treatment plan and risks, the person or the guardian voluntarily signs the informed consent, is willing to accept the clinical trial, and cooperates with the follow-up.
Exclusion criteria
Exclusion criteria: 1. The original infection, eczema, ulcer and other lesions at the lesion site that may affect the therapeutic effect, and those with other pigmented diseases such as nevus of Ota; 2. The patient has a history of epilepsy in the past six months or the condition is not controlled; 3. Allergic to porphyrin and analogs, allergic constitution; 4. Scar constitution; 5. History of sun exposure in the past 3 months; 6. The patient has abnormal electrocardiogram, structural heart disease, abnormal liver function, women who are pregnant or planning to conceive, and other potential diseases that may affect the treatment; 7. Patients who are participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical efficiency;pathologic features;Erythema blanching rate; | — |
Countries
China
Contacts
Public ContactZhang Yuyan
Shanghai Ninth People's Hospital, Shanghai Jiaotong University School Of Medicine
Outcome results
None listed