Breast cancer
Conditions
Interventions
Experimental group:Intravenous injection of 0.3 mCi/kg of 99m Tc-Dar2 injection
Sponsors
Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 70 years, and pathological diagnosis can be obtained by surgery or biopsy; 2. Clinical diagnosis or diagnosis of breast cancer; 3. Biopsy has confirmed tumor in some organs; 4. Informed consent must be signed by the subject or his/her legal guardian or caregiver; 5. If necessary, the subject can be accompanied by nursing staff; 6. Prior to any evaluation, the subject or his or her legal representative understands and signs a written informed consent; 7. Female subjects shall have medical records showing that they have been surgically sterilized (such as hysterectomy, bilateral oophorectomy or tubal ligation) or have been menopausal for more than one year; If fertility is still available, isolation contraception should be used during the study period; 8. Willing and able to cooperate with all projects of this study.
Exclusion criteria
Exclusion criteria: 1. Suffering from gastrointestinal, cardiovascular, renal, hematological, endocrine, respiratory, immune deficiency or other serious diseases; 2. Has been exposed to ionizing radiation outside the scope of this study in the past year due to other clinical medical or scientific needs, resulting in an annual radiation exposure of more than 50 mSv; 3. History of drug or alcohol abuse; 4. Pregnant or breastfeeding women; 5. Poor venous condition, unable to tolerate repeated venipuncture; 6.Treatment with an experimental drug or device (whose efficacy or safety is not clear) within 1 months; 7. May be allergic to 99mTc-Dar2 injection; 8. Any conditions that may cause or potentially cause harm in any link related to the test according to the research leader.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Integrin a6 expression level; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tumor metastasis; | — |
Countries
China
Contacts
Public ContactSong Erwei
Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University
Outcome results
None listed