A randomized controlled study of repetitive transcranial magnetic stimulation and repetitive peripheral magnetic stimulation in the treatment of upper limb motor dysfunction in post-stroke patients

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100049890

Enrollment

Unknown

Registered

2021-08-10

Start date

2021-08-20

Completion date

Unknown

Last updated

2022-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Central group:10Hz repetitive transcranial magnetic stimulation was given to the affected primary motor cortex

Peripheral group:Erb point 10Hz repetitive peripheral magnetic stimulation was given to the affected upper limb

Eligibility

Sex/Gender

All

Age

35 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria in "Key Points for the Diagnosis of Various Major Cerebrovascular Diseases in China 2019" and confirmed by CT or MRI; 2. The first onset, or a personal history of cerebrovascular disease but no residual neurological dysfunction; 3. The vital signs are stable, the consciousness is clear, can cooperate with the rehabilitation training, and can clearly express the training feeling; 4. Brunnstrom stage II to IV of the upper limb on the affected side; 5. Aged 35 to 75 years; 6. The course of the disease is 2 weeks to 6 months; 7. Improved Ashworth < grade 2; 8. The patient himself or his family signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Other intracranial diseases such as traumatic brain injury, encephalitis, etc. in the past, or the recent progressive aggravation of cerebrovascular disease; 2. Epilepsy patients or epilepsy family patients; 3. Combined with serious primary diseases such as heart, lung, liver, kidney, and hematopoietic system; 4. Those who cannot complete the index assessment, such as severe aphasia, audio-visual impairment, illiteracy, etc.; 5. There are pacemakers or cochlear implants, implanted devices (such as deep brain stimulators, ventriculoperitoneal shunts) and skull defects; 6. Upper limb motor dysfunction caused by trauma or peripheral nerve injury; 7. Can not tolerate magnetic stimulation.

Design outcomes

Primary

Measure	Time frame
resting motor threshold;Mean square mean of surface EMG signal during maximal isometric contraction (MIVC) of biceps and triceps;Fugl-Meyer Assessment-Upper Extremities;Wolf motor function test;modified Barthel Index;	—

Countries

China

Contacts

Public ContactWang Min

First Affiliated Hospital of Bengbu Medical College

1213484075@qq.com+86 15178368168

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026