hypertension
Conditions
Interventions
Experimental group:Hydrogen oxygen mixture
Sponsors
Shandong First Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for hypertension in the Chinese Guidelines for the Prevention and Treatment of Hypertension (Revised 2018); 2. Aged >18 years old; 3. Use <=2 kinds of antihypertensive drugs; 4. Patients voluntarily participated in the experiment and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Take anti-inflammatory and antioxidant drugs within 3 months before enrollment; 2. Patients with a history of chronic diseases include serious chronic diseases such as coronary heart disease, diabetes, malignant tumors, abnormal liver and kidney function, rheumatic immune diseases, hyperuricemia, abnormal thyroid function, asthma, depression, etc.; 3. Pregnant or lactating women; 4. AIDS, syphilis patients; 5. Poor compliance or inability to cooperate with examinations and affect clinical investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24-hour arterial blood pressure systolic blood pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Oxidative stress index;Inflammatory index;vascular endothelial function;24h ambulatory blood pressure related indexes;systemic vascular resistance; | — |
Countries
China
Contacts
Public ContactQin Shucun
Shandong First Medical University
Outcome results
None listed