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Effect of individualized embryo transfer based on endometrial receptivity test on clinical outcome of embryo implantation in patients with Preimplantation Genetic Testing: a multicenter, randomized, controlled, open-label clinical trial

Effect of individualized embryo transfer based on endometrial receptivity test on clinical outcome of embryo implantation in patients with Preimplantation Genetic Testing: a multicenter, randomized, controlled, open-label clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100049841
Enrollment
Unknown
Registered
2021-08-10
Start date
2022-03-01
Completion date
Unknown
Last updated
2022-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility

Interventions

controll group :No endometrial receptivity test and conventional time embryo transfer

Sponsors

Xiangya Hospital, Central South University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 43 Years

Inclusion criteria

Inclusion criteria: 1. Women aged 20 to 43 years; 2. BMI index 18-25kg/m2; 3. Comply with PGT treatment, and have one or more frozen D5/6 blastocysts that can be transplanted, and the blastocyst grade inner cell mass (ICM) >= grade B; 4. The ovarian reserve function test parameters meet 2 of the following 3 items: FSH=1.2ng/mL, AFC>=5.

Exclusion criteria

Exclusion criteria: 1. Uterine lesions that may affect implantation (including history of intrauterine adhesions, endometrial polyps, endometritis, endometrial tuberculosis, endometrial hyperplasia, thin endometrium, submucosal fibroids, adenomyosis ), uterine malformation; 2. Untreated severe hydrosalpinx with evidence of hydrosalpinx and uterine regurgitation; 3. Untreated serious medical and surgical diseases; 4. Immune system diseases that affect embryo implantation and pregnancy outcomes, such as positive anticardiolipin antibodies, or active rheumatic immune system diseases (such as systemic lupus erythematosus, Hashimoto's thyroiditis, Sj?gren's syndrome, multiple sclerosis, Crohn's disease); 5. Any situation that other researchers consider unsuitable to participate in this study, such as mental factors, etc.

Design outcomes

Primary

MeasureTime frame
Intrauterine clinical pregnancy rate;

Secondary

MeasureTime frame
embryo implantation rate;Time to pregnancy;ongoing clinical pregnancy rate;miscarriage rate;live birth rate;time to live birth;End of pregnancy time;

Countries

China

Contacts

Public ContactLi Yanping

Xiangya Hospital, Central South University

liyanp@csu.edu.cn+86 13607317798

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026