infertility
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Women aged 20 to 43 years; 2. BMI index 18-25kg/m2; 3. Comply with PGT treatment, and have one or more frozen D5/6 blastocysts that can be transplanted, and the blastocyst grade inner cell mass (ICM) >= grade B; 4. The ovarian reserve function test parameters meet 2 of the following 3 items: FSH=1.2ng/mL, AFC>=5.
Exclusion criteria
Exclusion criteria: 1. Uterine lesions that may affect implantation (including history of intrauterine adhesions, endometrial polyps, endometritis, endometrial tuberculosis, endometrial hyperplasia, thin endometrium, submucosal fibroids, adenomyosis ), uterine malformation; 2. Untreated severe hydrosalpinx with evidence of hydrosalpinx and uterine regurgitation; 3. Untreated serious medical and surgical diseases; 4. Immune system diseases that affect embryo implantation and pregnancy outcomes, such as positive anticardiolipin antibodies, or active rheumatic immune system diseases (such as systemic lupus erythematosus, Hashimoto's thyroiditis, Sj?gren's syndrome, multiple sclerosis, Crohn's disease); 5. Any situation that other researchers consider unsuitable to participate in this study, such as mental factors, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intrauterine clinical pregnancy rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| embryo implantation rate;Time to pregnancy;ongoing clinical pregnancy rate;miscarriage rate;live birth rate;time to live birth;End of pregnancy time; | — |
Countries
China
Contacts
Xiangya Hospital, Central South University