general anesthesia
Conditions
Interventions
Experimental group:Pretreatment with nalbuphine 0.1mg/kg (1mg/ml) was given 150 seconds before the use of fentanyl
Control group:Saline Solution 0.1 mL /kg was used as control 150 seconds before the use of fentanyl
Sponsors
Department of Anesthesiology, Zhongshan Ophthalmic Center, Sun Yat-Sen University
Eligibility
Sex/Gender
All
Age
3 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Aged 3 to 12 years; 2. ASA I-II grade; 3. Patients undergoing elective ophthalmic surgery.
Exclusion criteria
Exclusion criteria: 1. Patients with open eye trauma, corneal ulcer perforation, and glaucoma; 2. Patients with neuropsychiatric developmental delay; 3. Patients who are allergic to nalbuphine or fentanyl; 4. Patients with respiratory tract infection or intracranial space-occupying lesions; 5. Those who are unable to cooperate with venipuncture and those with language and communication disorders; 6. The patient is participating in other clinical research, the guardian refuses to participate, and the investigator considers it inappropriate to participate in other situations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall incidence of fentanyl-associated cough; | — |
Secondary
| Measure | Time frame |
|---|---|
| complications;Vital Signs; | — |
Countries
China
Contacts
Public ContactGan Xiaoliang
Zhongshan Ophthalmic Center, Sun Yat-Sen University
Outcome results
None listed