IgA nephropathy
Conditions
Interventions
control group:Telmisartan tablets
Experimental group:Huai Qi Huang Granules+Telmisartan tablets
Sponsors
Xiyuan Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. The diagnosis was IgA nephropathy, and the pathologic reports of renal perforation were reported in all cases; 2. aged 18 to 50 years; 3. Moderate proteinuria(24-hour urinary protein quantity is between 1.0-2.5g)accompanied or not accompanied by microscopic hematuria; 4. CKD1-2 (GFR>=60ml/min/1.73m2); 5. TCM syndrome differentiation accords with deficiency of Qi and Yin 6. Non-dialysis patients with infection, acidosis, electrolyte disturbance, hypertension and other aggravating factors are effectively controlled and the condition is stable. The BP is be effectively controlled in 140/90mmHg,Potassium is in the normal range; 7. Voluntarily accept this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.The age is less than 18 years old or more than 50 years old; 2.GFR<=60ml/min/1.73m2; 3.Patients with mild or severe proteinuria (24-hour urine protein quantification less than 1.0g or more than 2.5g) and nephrotic syndrome; 4.Various secondary IgA nephropathy; 5.Those who have used glucocorticoids, immunosuppressants or Tripterygium wilfordii preparation within three months; 6.Hypotension patients with blood pressure <=90/60mmHg; 7.Severe diseases of the heart, brain, liver and hematopoietic system, or other serious diseases affecting their survival; 8.Unilateral or bilateral renal artery stenosis; 9.Breast-feeding, pregnant or planning pregnancy during the study period; 10.Attending to participate in another clinical researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urine protein quantitation for 24 hours; | — |
Secondary
| Measure | Time frame |
|---|---|
| Routine urine;Traditional Chinese Medicine symptom score;renal function;Blood fat;Routine blood;Liver function; | — |
Countries
China
Contacts
Public ContactZhang Yu
Xiyuan Hospital, China Academy of Chinese Medical Sciences
Outcome results
None listed