Osteoarthritis of the knee
Conditions
Interventions
group A:The concentration of ropivacaine was 0.2% used for ACB+ IPACK
group B:The concentration of ropivacaine was 0.25% used for ACB+ IPACK
group C:The concentration of ropivacaine was 0.3% used for ACB+ IPACK
Sponsors
Anaesthetic surgery center, West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients requiring unilateral initial TKA surgery due to severe knee osteoarthritis; 2. Aged 40 to 80 years; 3. Body mass index 20~35 kg/m2; 4. The American Society of Anesthesiologists (ASA) classification (anesthesia risk assessment) is I ~ III level.
Exclusion criteria
Exclusion criteria: 1. Those who are allergic to anesthetics and sulfonamides; 2. There is moderate or higher knee joint deformity (varus and flexion) and joint stiffness; 3. Those who drink heavily or take opioids for a long time; 4. Language barriers and those who cannot complete the numerical rating scales (NRS) of pain; 5. Patients with neuropathy on the side of the operation; 6. Mental patients; 7. Those with previous peptic ulcer.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative dosage of remedial morphine hydrochloride; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to first postoperative analgesia;VAS pain score;Range of knee motion;Quadriceps strength;Time to first straight leg raise;The duration of hospital stay;Incidence of postoperative complications; | — |
Countries
China
Contacts
Public ContactYang Jing
West China Hospital, Sichuan University
Outcome results
None listed