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Observation on the Efficacy of Shenge Powder on the Patients of Chronic Heart Failure

Observation on the Efficacy of Shenge Powder on the Patients of Chronic Heart Failure

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100049790
Enrollment
Unknown
Registered
2021-08-09
Start date
2021-08-16
Completion date
Unknown
Last updated
2022-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic heart failure

Interventions

Sponsors

Nanxiang Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Western medicine diagnostic criteria: have a history of coronary heart disease, and meet the above-mentioned diagnostic criteria for chronic heart failure; 2. TCM diagnostic criteria: formulated with reference to the relevant content of "Shanghai Traditional Chinese Medicine Diseases and Syndrome Diagnosis and Treatment Routine" (Second Edition), namely main symptoms: palpitations, shortness of breath and fatigue, asthma with movement, conscious fear of cold, and low temperature of hands and feet. Secondary symptoms: oliguria and edema, abdominal distension, loose stools, and pale complexion. Tongue pulse: The tongue is fat or has tooth marks, and the pulse is thin or late. The main symptoms must have 2 items, and the secondary symptoms have 2 items. Combined with the tongue and pulse, the diagnosis can be established; 3. Aged 45 to 85 years old; 4. Cardiac function classification: according to the New York Heart Association (NYHA) cardiac function classification method, the cardiac function is II to III.

Exclusion criteria

Exclusion criteria: 1. Those with bronchial asthma, chronic bronchitis, pulmonary heart disease, chronic obstructive pulmonary disease; 2. Those with unstable blood pressure control; 3. Patients with acute cardiac insufficiency; 4. Patients with severe liver and kidney dysfunction and heart failure due to failure of important organs such as kidney and liver; 5. Patients with serious primary diseases such as endocrine system and hematopoietic system; 6. Pregnant or lactating women; 7. Those with allergic constitution or history of allergies; 8. Patients with mental disorders and unwilling to cooperate; patients with poor compliance, and those who interrupt the treatment before the prescribed observation period cannot judge the curative effect.

Design outcomes

Primary

MeasureTime frame
TCM symptom score;NYHA functional classification;Six minute walking test (6MWT);

Secondary

MeasureTime frame
Brain natriuretic peptide;Homocysteine;Interleukin-6;Tumor necrosis factor-a(TNF-a);Nuclear factor kappa-B;High-sensitivity C-reactive protein;High-Sensitivity Troponin T;Cystatin C;Electrocardiogram;Echocardiography;Quality of life assessment;TCM Syndrome Score;

Countries

China

Contacts

Public ContactZhou Li

Nanxiang Hospital

babyzhouli@hotmail.com+86 13918690782

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026