Trigeminal Neuralgia
Conditions
Interventions
Remimazolam deep anesthesia group:0.2-0.4mg/kg remazolam was slowly injected during induction of anesthesia. After induction intubation, the initial pump rate of remazolam was 1 mg/kg/h, and the infus
Remimazolam traditional anethesia group:0.2-0.4mg/kg remazolam was slowly injected during induction of anesthesia. After induction intubation, the initial pump rate of remazolam was 1 mg/kg/h, and the
Propofol deep anesthesia group:2.0-2.5mg/kg propofol was slowly injected during induction of anesthesia. After induction intubation, the initial pump rate of the propofol was 1 mg/kg/h, and the infusi
Propofol traditional anethesia group:2.0-2.5mg/kg propofol was slowly injected during induction of anesthesia. After induction intubation, the initial pump rate of the propofol was 1 mg/kg/h, and the
Sponsors
The Second Xiangya Hospital of Central South University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years old; 18kg/m2<BMI<30kg/m2; 2. Patients diagnosed with trigeminal neuralgia and undergoing selective percutaneous microballoon trigeminal ganglion compression; 3. Clearly understand the experimental process and voluntarily participate in the study, and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with difficult airway; 2. Patients with severe anemia or severe thrombocytopenia; 3. Severe liver and kidney damage; 4. Hypertensive patients whose blood pressure is not satisfactorily controlled by antihypertensive drugs (systolic blood pressure >= 160 mmHg, and/or diastolic blood pressure >= 100 mmHg); 5. Systolic blood pressure<=90mmHg; 6. Preoperative cardiac ultrasonography found obvious abnormal wall motion, aortic valve disease and other serious valve disease, preoperative intra-aortic balloon counterpulsation (IABP), and obvious preoperative arrhythmia; 7. Women who are pregnant or breastfeeding; 8. Patients allergic to benzodiazepines and opioids; 9. Participated in clinical trials of other drugs as subjects within the past 3 months; 10. The investigators believe that patients who are not suitable to participate in this trial; 11. Those who suffer from mental system diseases (schizophrenia, mania, bipolar disorder, insanity, etc.) and have a history of long-term use of psychotropic drugs and cognitive dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemodynamics; | — |
Countries
China
Contacts
Public ContactXiao Yanying
Department of Anesthesiology, The Second Xiangya Hospital, Central South University
Outcome results
None listed