endoscopic retrograde cholangiopancreatography
Conditions
Interventions
remimazolam group:No Intervention
midazolam group:No
Sponsors
Renmin Hospital of Wuhan University
Eligibility
Sex/Gender
All
Age
65 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Subjects receiving ERCP; 2. Male or female, ASA class I-II, age 65~ years old; 3. Body mass index (BMI) >=18 and =10 and =90% when inhaling air; SBP>=90 mmHg; DBP>=60 mmHg; heart rate should be >=60 and <=120 times/min; 6. Be able to understand the procedures and methods of this research, be willing to sign the informed consent and strictly follow the clinical research protocol to complete this research.
Exclusion criteria
Exclusion criteria: 1. Elderly patients with epilepsy, glaucoma and enlarged prostate; 2. Those with contraindications to deep sedation/general anesthesia or those who have had a history of sedation/anesthesia accident in the past; 3. Patients who are judged to be difficult to manage the respiratory tract (modified Markov score is grade IV), and the basic blood oxygen saturation is less than 90%; 4. Those with contraindications to routine endoscopic operation; 5. Patients who are considered by the investigator to have any other factors that are not suitable for participating in this clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| success rate of procedure sedation; | — |
Secondary
| Measure | Time frame |
|---|---|
| time to adequate sedation;time to fully alert;incidence of respiratory depression;the requirement for sedative rescue medication ( propofol ), the number of dose and total additional dose were compared between the two groups;pain score;patient satisfaction score; | — |
Countries
China
Contacts
Public ContactZhang Fan
Department of Anesthesiology, Renmin Hospital of Wuhan University
Outcome results
None listed