Depression, Bipolar disorder
Conditions
Interventions
Sponsors
Beijing Anding Hospital affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. The selected patients are 18-60 years old, gender-neutral, right-handed; meet the diagnostic criteria of the Diagnostic and Statistical Manual of Mental Disorders: (Diagnostic and Statistical Manual of Mental Disorders, DSM-IV) depressive episode, bipolar I type disorder, which is currently the diagnostic criteria for depressive episodes and schizophrenia; 2. Depressed patients meet the Hamilton Depression Scale (HAMD-17) score >= 17; 3. Patients included in this experimental study sample should stop taking benzodiazepines 8 hours before electrophysiological assessment; 4. Participants who participated in this study signed the informed consent form of this experiment to be included in this study.
Exclusion criteria
Exclusion criteria: 1. There is a serious mental disorder or neurological disease other than the diseases in the inclusion criteria, or there is alcohol or substance dependence, or there is a language ability disorder and cannot effectively complete the test; 2. Mental retardation; 3. Impulsive, excited, uncooperative; 4. Pregnant or lactating women; 5. Diagnosed with epilepsy, or the individual has a history of epileptic seizures, or the patient's first-degree relatives have a history of epilepsy, taking drugs associated with an increased risk of epilepsy or are on medication; 6. Has undergone brain surgery with the presence of intracranial implants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| EEG resting-state neural oscillations;EEG task state neural oscillations;Magnetic resonance spectroscopy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time-frequency analysis of EEG features;Correlation analysis of data with clinical characteristics; | — |
Countries
China
Contacts
Public ContactJia Lina
Beijing Anding Hospital
Outcome results
None listed