craniocerebral surgery
Conditions
Interventions
group one:Lidocaine was injected above the cuff
group two:Lidocaine was injected under the cuff
group three:Normal saline was injected above the cuff
group four:Normal saline was injected under the cuff
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients undergoing elective craniocerebral surgery under general anesthesia intubation, explained the scheme to the patients and obtained their consent. ASA grade I-III, aged 20-60 years, BMI 18-30 kg / m2.
Exclusion criteria
Exclusion criteria: 1. Allergy to anesthetics; 2. Recent history of upper respiratory tract infection, chronic obstructive disease, and asthma; 3. Preoperative airway classification 3-4, restricted head and neck back, difficulty in opening the mouth and other suspected difficult intubation; 4. History of cardiovascular diseases such as coronary heart disease, myocarditis, myocardial infarction, Adams syndrome (acute cardiogenic cerebral ischemic syndrome), pre-excitation syndrome, severe heart block (including sinoatrial, atrial Ventricular and intraventricular conduction block), etc., severe liver and kidney insufficiency; 5. Patients with severe intracranial hypertension, brain herniation or coma; 6. Preoperative use of beta-blockers; 7. History of laryngeal and bronchial surgery; 8. The tumor is close to the respiratory and circulatory centers, and the endotracheal tube cannot be removed due to the inability to restore normal breathing and choking reflex after the operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence and severity of cough during extubation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Systolic blood pressure, diastolic blood pressure, heart rate and SpO2 immediately after extubation;VAS score of pharyngeal pain 24 hours after operation; | — |
Countries
China
Contacts
Public ContactLi Yu
West China Hospital, Sichuan University
Outcome results
None listed