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Clinical study of 3D printed artificial vertebral body in treatment of ossification of posterior longitudinal ligament of cervical spine

Clinical study of 3D printed artificial vertebral body in treatment of ossification of posterior longitudinal ligament of cervical spine

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100049707
Enrollment
Unknown
Registered
2021-08-08
Start date
2021-09-01
Completion date
Unknown
Last updated
2022-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ossification of the posterior longitudinal ligament

Interventions

Anterior vertebral body subtotal resection titanium cage autologous bone grafting combined with steel plate vertebral reconstruction group:Anterior vertebral body subtotal resection titanium cage auto
Anterior vertebral subtotal 3D printing titanium trabecular artificial vertebral body combined with steel plate vertebral body reconstruction group:Anterior vertebral subtotal 3D printing titanium tra

Sponsors

Department of Orthopedics, Chongqing University Three Gorges Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. During the period from September 1, 2020 to August 31, 2021, aged 18-75 years, diagnosed with symptomatic cervical OPLL, and underwent anterior posterior longitudinal ligament ossification and vertebral subtotal surgery in our hospital; 2. The main evaluation indicators include imaging manifestations, neurological function, and complications before and after surgery; 3. Follow-up period of at least 1 year; 4. No history of spine (cervical, thoracic, lumbar) surgery; no history of cervical spine trauma, infection and tumor; 5. Symptoms are caused by cervical OPLL compressing the spinal cord.

Exclusion criteria

Exclusion criteria: 1. Continuous OPLL ossification compresses spinal cord >3 segments; 2. The width of the ossification exceeds the uncinate joint; 3. Complete loss of spinal cord function; 4. The tumor in the front of the neck affects those exposed.

Design outcomes

Primary

MeasureTime frame
JOA score (Japanese Orthopaedic Association Evaluation Treatment Score);Spinal canal invasion rate of OPLL;Visual Analog Score;Nerve function recovery rate;

Secondary

MeasureTime frame
C2 - C7 Angle;

Countries

china

Contacts

Public ContactChen Jian

Department of Orthopedics, Chongqing University Three Gorges Hospital

284262176@qq.com+86 15123420829

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026