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Effect of Lidocaine on CD4 + / CD8 + T cells and body stress in patients undergoing gastric cancer surgery

Effect of Lidocaine on CD4 + / CD8 + T cells and body stress in patients undergoing gastric cancer surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100049694
Enrollment
Unknown
Registered
2021-08-08
Start date
2021-08-10
Completion date
Unknown
Last updated
2022-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Experimental group:Intravenous Lidocaine
Control group:Intravenous physiological saline

Sponsors

First Affiliated Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. American Society of Anesthesiologists (ASA) grades I-III; 2. Patients who are scheduled to undergo radical gastrectomy under general anesthesia.

Exclusion criteria

Exclusion criteria: 1. Severe hepatic and renal insufficiency; 2. Severe heart block; 3. Lidocaine allergy history; 4. Long-term use of opioid analgesics, drug abuse, alcohol abuse and history of mental illness; 5. Refuse to participate in this experiment.

Design outcomes

Primary

MeasureTime frame
CD4+T cell;CD8+T cell;tumor recurrence rate;—

Secondary

MeasureTime frame
gamma-interferon;IL-2;epinephrine;norepinephrine;cortisol;—

Countries

China

Contacts

Public ContactJi Fuhai

The First Affiliated Hospital of Soochow University

jifuhaisuda@163.com+86 13656207331

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026