delirium
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Elective knee and hip replacement surgery under spinal anesthesia; 2. Aged >= 65 years; 3. ASA I-III grade; 4. Voluntarily sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Preoperative MMSE score <23 points; 2. Concomitant neurological diseases: Alzheimer's disease, vascular dementia and other diseases that affect the cognitive function of patients; 3. Blind, deaf, illiterate and other people who cannot communicate normally; 4. Investigators who have participated in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complement; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammatory cytokines;Drug use;Postoperative pain; | — |
Countries
China
Contacts
Eastern Theater General Hospital