postoperative sleep disturbance
Conditions
Interventions
Group 1:None
Group 2:Remazolam 0.5mg/kg nasal spray
Group 3:Remazolam 0.75mg/kg nasal spray
Group 4:Remazolam 0.2mg/kg/h pump injection
Group 5:Remazolam 0.4mg/kg/h infusion
Sponsors
Plastic Surgery Hospital of Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing maxillofacial surgery under general anesthesia and endotracheal intubation, no gender restrictions, aged 18-40 years, ASA I or II. 2. Stay in the anesthesia recovery room on the first night after surgery.
Exclusion criteria
Exclusion criteria: 1. Have other system diseases, such as congenital heart disease, hypertension, history of epilepsy. 2. Patients with severe sleep apnea syndrome, depression, use of sleep aids and sedative and analgesic drugs, foreign bodies in the respiratory tract, tumors, polyps, abscesses, and upper respiratory tract infections in the past 2 weeks. 3. Patients with hearing and speech impairment who cannot cooperate and refuse to join the group.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sleep rhythm; | — |
Secondary
| Measure | Time frame |
|---|---|
| PSQI;Total length of hospitalization and total cost;Medication complications; | — |
Countries
China
Contacts
Public ContactWang Ye
Chinese Academy of Medical Sciences Peking Union Medical College Plastic Surgery Hospital
Outcome results
None listed