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Neuroimaging research of structural and functional changes of nucleus accumbens in the transition from acute to chronic pain after surgery

Neuroimaging research of structural and functional changes of nucleus accumbens in the transition from acute to chronic pain after surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100049631
Enrollment
Unknown
Registered
2021-08-07
Start date
2021-08-10
Completion date
Unknown
Last updated
2023-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic postsurgical pain (CPSP)

Interventions

case series:none

Sponsors

Xuzhou Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients aged 45-65 years for elective thoracotomy.

Exclusion criteria

Exclusion criteria: 1. Acute and chronic pain symptoms lasting more than 1 week within 12 months; 2. Postoperative radiotherapy and chemotherapy are required; 3. Carrying magnetic metal plants or electronic products into things; 4. Neuropsychiatric diseases; 5. Insufficiency of important organs such as liver and kidney; 6. Visual and auditory language insufficiency.

Design outcomes

Primary

MeasureTime frame
BOLD signal and functional connectivity between shell and core of nucleus accumbens;Functional connectivity between nucleus accumbens and other brain region;—

Secondary

MeasureTime frame
Structure connectivity between nucleus accumbens and other brain region;Nucleus accumbens volume;Visual analogue scale;Short form McGill pain questionnaire;Neuropathic pain scale;Pain catastrophizing scale;Beck depression inventory (BDI);—

Countries

China

Contacts

Public ContactCao Junli

Xuzhou Medical University

caojl0310@aliyun.com+86 15162160809

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026