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A randomized, controlled, double-blind study of alfentanil combined with cyclopofol to improve the quality of sedation and recovery during painless gastrointestinal endoscopy

A randomized, controlled, double-blind study of alfentanil combined with cyclopofol to improve the quality of sedation and recovery during painless gastrointestinal endoscopy

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100049609
Enrollment
Unknown
Registered
2021-08-06
Start date
2021-08-18
Completion date
Unknown
Last updated
2022-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrointestinal disease

Interventions

Group 1:Ciprofol intravenous injection

Sponsors

Gansu Provincial Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-65 years; ASA score is I or II; 2. Patients who plan to undergo painless digestive endoscopy; 3. SPO2>=92% when breathing air before surgery; 180mmg>=SBP>=90mmHg; 100>=DBP>=50mmHg; 4. 18kg/m^2<=BMI<=28kg/m^2; 5. Before the trial, understand the nature, significance, possible benefits, possible inconveniences and potential dangers of the trial in detail, understand the research procedures and voluntarily sign the informed consent in writing.

Exclusion criteria

Exclusion criteria: 1. Requires complex endoscopic diagnosis and treatment techniques; 2. Patients who are judged to be difficult to manage the respiratory tract (modified Markov classification IV); 3. Those who are allergic to or have contraindications to benzodiazepines, opioids, propofol, and propofol emulsion injection excipients; 4. Participated in clinical trials of other drugs as subjects within the past 3 months; 5. Those who cannot obtain informed consent, or those who are considered unsuitable by the investigator to participate in this trial.

Design outcomes

Primary

MeasureTime frame
Incidence of intraoperative adverse events;Anesthesia recovery time;

Countries

China

Contacts

Public ContactYan Wenjun
871523533@qq.com+86 13893370700

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026