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Analysis of risk factors and related single nucleotide gene polymorphisms of postoperative analgesia in patients with hepatobiliary surgery

Risk factors analysis and related SINGLE AAnalysis of risk factors and related single nucleotide gene polymorphisms of postoperative analgesia in patients with hepatobiliary surgerynucleotide gene polymorphisms of postoperative analgesia in hepatobiliary surgery patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100049607
Enrollment
Unknown
Registered
2021-08-06
Start date
2021-08-16
Completion date
Unknown
Last updated
2022-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

case series:None

Sponsors

He'nan Province People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-75 years; 2. Patients with elective hepatobiliary surgery; 3. ASA classification I-III; 4. In line with ethics, the patients were tested voluntarily and signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating patients; 2. Patients with severe renal dysfunction (severe renal dysfunction: Cr clearance <30 ml/min); 3. Abnormal history of anesthesia; 4. History of allergy to drugs such as anesthetics or opioids; 5. Communication impairment; 6. History of chronic pain, alcohol dependence, mental illness; 7. Long-term use of sedative and/or analgesic and/or anxiolytic, depressive and/or non-steroidal analgesics; 8. Use of monoamine oxidase inhibitors and/or antidepressants and/or antiepileptic drugs within 15 days before surgery; 9. Use of sedative and/or analgesic and/or antipruritic drugs within 24 hours before surgery; 10. Other patients who are not considered suitable to participate in this trial.

Design outcomes

Primary

MeasureTime frame
single nucleotide polymorphism;visual analogue scale scoring;

Countries

China

Contacts

Public ContactZhang Jiaqiang

He'nan Province People's Hospital

hnmzxh@163.com+86 13937121360

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026