Research on individualized treatment of local recurrent rectal cancer patients based on organoid model

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100049600

Enrollment

Unknown

Registered

2021-08-06

Start date

2021-09-01

Completion date

Unknown

Last updated

2022-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rectal cancer

Interventions

Group 1:none

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Locally recurrent rectal cancer with or without distant metastasis diagnosed by pathology; 2.Resection of local recurrent lesions is feasible after multidisciplinary discussion. 3.Complete follow-up data; 4.No infectious diseases such as hepatitis B, hepatitis C, HIV, or syphilis; 5.Volunteer for this study, have written informed consent.

Exclusion criteria

Exclusion criteria: 1. Hereditary colorectal cancer; 2. There is a history of malignant tumor in the past. 3. Incomplete collection of clinical data. 4. The patient is participating in other clinical trials.

Design outcomes

Primary

Measure	Time frame
The size and quantity of organoids; Half maximum inhibitory concentration(IC50);Progression free survival;Objective Response Rate; Clinical Benefit Response;	—

Countries

China

Contacts

Public ContactGu Jin

Peking University Shougang Hospital

zlgujin@126.com+86 13801180717

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026