Severe burns
Conditions
Interventions
experimental group:Cell transplantation
Sponsors
Burn Department of the First Affiliated Hospital of Army Medical University, PLA
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Voluntary and clinical treatment of patients with insufficient skin source; 2. The selected patients are voluntary and sign the "informed consent"; 3. Aged 18-60 years old; 4. Very severe burn patients: burn area >= 50% TBSA, and scalp burn patients.
Exclusion criteria
Exclusion criteria: 1. Patients with a clear history of malignant tumors, AIDS, autoimmune diseases, and organ transplantation; 2. Patients who are pregnant or breastfeeding; 3. Those who have had myocardial infarction and cerebrovascular accident within 6 months; 4. The investigator's comprehensive assessment believes that the patient and his family have poor willingness to treat, which may lead to the risk of trial termination; 5. The researcher comprehensively evaluates the possible situations related to the poor quality of life caused by scars after the patients and their families cannot receive successful treatment; 6. Patients with poor systemic condition, multiple organ failure, severe systemic infection and severe wound infection, etc., and the investigators comprehensively evaluate patients who believe that the condition is unstable or the wound has no ability to receive skin (it is believed that the wound cannot survive after cell transplantation); 7. Other conditions deemed inappropriate by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| re-epithelialization;Wound healing rate;Wound healing time;Time in BICU;Quality of wound healing; | — |
Countries
China
Contacts
Public ContactZhan Rixing, Luo Gaoxing, Yu Shicang
the First Affiliated Hospital of Army Medical University
Outcome results
None listed