Subarachnoid hemorrhage
Conditions
Interventions
Test group:Intravascular hypothermia therapy
Sponsors
Henan Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged over 18 years old; 2. The first CT scan or lumbar puncture on admission confirmed the diagnosis of subarachnoid hemorrhage; 3. Routinely accepted digital subtraction angiography (DSA) or CTA within 72 hours after hospitalization to diagnose intracranial aneurysm; 4. Received intracranial aneurysm craniotomy, interventional embolization or compound surgery within 72 hours; 5. Hunt-Hess classification level III or above; 6. The patient's family signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Over 80 years old; 2. Patients with systemic inflammatory response syndrome or sepsis at the time of enrollment; 3. Have a history of hematological diseases, bleeding constitution, coagulation dysfunction, check prothrombin time (PT)>15s, activated partial thromboplastin time (APTT)>40s, international normalized ratio (INR)>1.4, platelet count (PLT)<100x10^9/L; 4. Major surgery or trauma history within the past three months; 5. A history of gastrointestinal ulcer in the past three months, and a history of urinary system bleeding in the past three weeks; 6. Intracerebral hemorrhage or myocardial infarction occurred in the past three months; 7. Pregnancy and lactation patients; 8. Patients with autoimmune diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Good prognosis rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Glasgow Coma Index Score;National Institutes of Health Neurological Impairment Score (NIHSS) score; | — |
Countries
Zhongguo
Contacts
Public ContactFeng Guang
Henan Provincial People's Hospital
Outcome results
None listed