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Effect of total intravenous anesthesia combined with transverse abdominal plane block on early postoperative cognitive function in middle-aged patients undergoing gynecological surgery

Effect of total intravenous anesthesia combined with transverse abdominal plane block on early postoperative cognitive function in middle-aged patients undergoing gynecological surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100049589
Enrollment
Unknown
Registered
2021-08-05
Start date
2018-01-01
Completion date
Unknown
Last updated
2022-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative cognitive dysfunction

Interventions

General anesthesia combined with transverse abdominal plane block group:transverse abdominal plane block

Sponsors

The Fourth Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
40 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Aged 40 to 60 years old; 2. Can communicate with testers normally; 3. Preoperative simple mental status scale (MMSE) > score 27; 4. American Society of Anesthesiologists (ASA) Grade I-II, BMI 20-25kg/m2; 5. Right-handed.

Exclusion criteria

Exclusion criteria: 1. disorders that affect cognitive function; 2. severe cardiopulmonary, liver and kidney dysfunction; 3. visual or sensory disorders; 4. speech disorders or severe hearing impairment.

Design outcomes

Primary

MeasureTime frame
Montreal Cognitive Assessment;alertness;orientation;executive control;mean reaction time;accuracy;—

Countries

China

Contacts

Public ContactWeiwei Wu

The Fourth Affiliated Hospital of Anhui Medical University

wuweiwei_wy@163.com+86 18856910051

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026