Effect of heated humidified high flow nasal cannula(HFNC) oxygen therapy in dyspnea patients with advanced cancer

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100049582

Enrollment

Unknown

Registered

2021-08-04

Start date

2019-04-09

Completion date

Unknown

Last updated

2022-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

advanced cancer

Interventions

intervention group:Using heated humidified high flow nasal cannula(HFNC) oxygen therapy

control group:Using conventional nasal catheter oxygen therapy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. aged between 18 and 80 years old; 2. meet the following five conditions: (1) patients with advanced solid cancer; (2) atients meeting grade 4 of the mMRC; (3) the curative treatment was not effective and palliative care was accepted; (4) Respiratory rate >30 times/min; (5) Oxygen index < 1:250. 3. Signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. patients were intolerant, irritable and uncooperative; 2. invasive assisted ventilation was needed for exacerbation of the disease; 3. patients abandoned treatment; 4. duration of hospital stay < 3d.

Design outcomes

Primary

Measure	Time frame
the degree of dyspnea;the degree of oral dryness;sleep quality;	—

Secondary

Measure	Time frame
PH;arterial partial pressure of oxygen;arterial partial pressure of carbon dioxide,PCO2;Respiratory rate;Heart rate;transcutaneous oxygen saturation;	—

Countries

China

Contacts

Public ContactDedong Ma

Department of Pulmonary and Critical Care Medicine, Qilu Hospital, Shandong University

ma@qiluhuxi.com+86 18560082806

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 14, 2026