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A prospective randomized controlled study on prevention of anastomotic leakage after laparoscopic radical resection of rectal cancer by serosal suture

A new technique to prevent anastomotic leakage after laparoscopic resection of rectal cancer

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100049568
Enrollment
Unknown
Registered
2021-08-03
Start date
2021-01-29
Completion date
Unknown
Last updated
2022-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rectal cancer

Interventions

Controlled group:Without special suture, others same as the experimental group
Experimental group:Take a 3-0 absorbable suture with a length of about 15cm, put two needles into the "dog's ear" on the side of the rectal stump, and put the needle out at the corresponding point of

Sponsors

Guangdong Provincia Hospital of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Older than 18 years old; (2) Preoperative imaging and colonoscopy confirmed or suspected rectal cancer; (3) The primary tumor can be removed completely; (4) Laparoscopic radical resection of rectal cancer / b colon cancer was performed, and double anastomosis technique was used for digestive tract reconstruction; (5) There was no indication of preoperative neoadjuvant chemoradiotherapy.

Exclusion criteria

Exclusion criteria: (1) Emergency operation due to obstruction, perforation or bleeding; (2) The patients with unresectable primary tumor due to too large tumor or close adhesion between tumor and surrounding tissue; (3) Patients who plan to have preventive or permanent colostomy after operation; (4) Preoperative neoadjuvant chemoradiotherapy; (5) The second operation was performed in patients with tumor recurrence; (6) History of colorectal cancer surgery; (7) The uterus, bilateral appendages and other pelvic organs should be removed; (8) American Society of anesthesiologists (ASA) grade IV or V, patients with severe heart, lung, liver and kidney diseases can not tolerate laparoscopic surgery.

Design outcomes

Primary

MeasureTime frame
Incidence of anastomotic leakage 30 days after operation;

Secondary

MeasureTime frame
Incidence of postoperative complications and 30 day mortality;operation time;Intraoperative blood loss;operative complicaiton;postoperative hospital stay;

Countries

China

Contacts

Public ContactDechang Diao

Guangdong Provincial Hospital of TCM

diaodechang223@163.com+86 13416119782

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026