Research on the Intervention Effect of Multi-mode Exercise on the Elderly with Mild Cognitive Impairment

Effect of exercise on individuals with mild cognitive dysfunction and its biology Mechanism Research

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100049556

Enrollment

Unknown

Registered

2021-08-02

Start date

2021-08-02

Completion date

Unknown

Last updated

2022-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild cognitive impairment

Interventions

Mild cognitive impairment exercise intervention group:multimode exercise intervention

Mild cognitive impairment stretch control group:stretch control

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Complaints of decreased memory and cognitive impairment, but did not meet the diagnostic criteria of dementia, Montreal cognitive assessment (MoCA) score = 24; 2.Aged >= 65 years, irregular exercise, Activity of Daily Living Scale (ADL) assessment <26, basic physical health, No organic diseases; 3.MRI T1-weighted sequence clinical diagnosis of hippocampal volume atrophy.

Exclusion criteria

Exclusion criteria: All kinds of exercise contraindications (cardiovascular disease, exercise disease, etc.), cognitive impairment drug use, MRI contraindications, etc.

Design outcomes

Primary

Measure	Time frame
Montreal cognitive assessment;	—

Secondary

Measure	Time frame
Digit Span Test Forward/ Backward;Symbol digit modalities test;Verbal fluence test;Trail Making Test;Logical memory test;Neurotrophic factors;hippocampal subfields volume;	—

Countries

China

Contacts

Public ContactYin Liqin

Hunan University of Technology

yin123liqin@163.com+86 13787335852

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026