Knee osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Male or female, 45-75 years old; 2. Diagnose knee osteoarthritis according to the American College of Rheumatology (ACR) criteria; 3. Radiological examination to confirm knee osteoarthritis (Lawrence grade I to III); 4. The average daily pain score is 40 points (0-100 points); 5. Symptoms for more than 6 months; 6. Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Can not walk; 2. Severe knee infection; 3. A history of trauma, ligament injury, fracture or surgery within 6 months, causing pain or functional problems (excluding a history of knee replacement); 4. There is a history of local tumor/malignant tumor in the knee joint; 5. Physical or laboratory findings suggestive of infection, the presence of an autoimmune disease or inflammatory arthritis; 6. Knee pain caused by radiculopathy/disc herniation; 7. Have end-stage disease or lower extremity deep vein thrombosis, cancer or cancer treatment-related edema, severe coagulation disorder, systemic hypertension, severe diabetes; 8. There is a history of pre-hormone therapy, hyaluronic acid injection or corticosteroid injection within 3 months; 9. Received acupuncture, electro-acupuncture, massage or physical therapy before 8 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Western Ontario and McMaster University Osteoarthritis Index scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| Arthritis Quality of Life Measurement Scale Simplified Scale (AIMS2-SF);The pain visual analogue scale (VAS);Baker anxiety scale (BAI);Baker Depression scale (BDI);Expectancy Questionnaire; | — |
Countries
China
Contacts
The First Affiliated Hospital of Henan University of Traditional Chinese Medicine