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Low-dose esketamine combined with propofol sedation for outpatient colonoscopy

Low-dose esketamine combined with propofol sedation for outpatient colonoscopy

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100049506
Enrollment
Unknown
Registered
2021-08-02
Start date
2021-08-01
Completion date
Unknown
Last updated
2022-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colon-related diseases

Interventions

Group S:S??????????0.15mg/kg
Group C:C???????????

Sponsors

The Sixth Affiliated Hospital of Guangzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 75 years; 2. ASA classification is between I-II; 3. BMI index (body mass index) does not exceed 40; 4. Able to sign the informed consent form independently.

Exclusion criteria

Exclusion criteria: 1. Known history of allergic reactions to the drugs planned for the study; 2. History of uncontrolled or severe hypertension; 3. Severe ischemic heart disease, mental illness, chronic pain, pregnancy, seizures, increased intracranial pressure; 4. Recent history of drug abuse or use of drugs that affect the central nervous system.

Design outcomes

Primary

MeasureTime frame
Cumulative dose of propofol;

Secondary

MeasureTime frame
Duration of colonoscopy;recovery time;Duration of PACU;patient satisfaction;endoscopist satisfaction;Incidence of nausea and vomiting;oxygen desaturation; severe oxygen desaturation;need for airway intervention;The first time use of vasoactive agents;The first time need of airway intercention;

Countries

China

Contacts

Public ContactHuang Yizhou

The Sixth Affiliated Hospital of Guangzhou Medical University

985380597@qq.com+86 15715213820

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026