Anesthesia effect
Conditions
Interventions
Control group:Serratus anterior plane block was not performed and remimazolam was not administered
Experimental group1:Bilateral serratus anterior plane block with 0.375% ropivacaine was performed under ultrasound guidance 30 min before anesthesia
Experimental group2:Anesthesia was induced by intravenous injection of remimazolam 7 mg, followed by continuous pump injection of 0.2 mg / kg / h
Experimental group3:Bilateral serratus anterior plane block with 0.375% ropivacaine was performed under ultrasound guidance 30 min before anesthesia. And anesthesia was induced by intravenous injectio
Sponsors
The First Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
All
Age
16 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Aged 16 to 50 years, weight 40-66 kg (BMI 18.5-23.9); 2. ASA classification I~II; 3. Sign the informed consent form with the patient.
Exclusion criteria
Exclusion criteria: 1. Severe heart, lung, liver, kidney dysfunction, abnormal coagulation function; 2. History of drug allergy, history of peptic ulcer, history of depression, history of long-term drinking or drug abuse; 3. There is a recent history of taking opioids; 4. History of postoperative nausea, vomiting or motion sickness; 5. Nausea or vomiting within 48 hours before surgery; 6. Taking psychotropic drugs (benzodiazepines, antidepressants, antiepileptics and antipsychotics).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Systolic blood pressure;Diastolic blood pressure;Mean arterial pressure;Heart rate;Pulse oxygen saturation;Incidence of hypotension;Pain score;Use of analgesic drugs;Operation time;Anesthesia time;Anesthesia recovery time;Abnormal conditions such as airway obstruction;Delirium assessment;tumor necrosis factor-a;C reactive protein;Time required to reach an Aldrete improvement score of 9; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time required to reach a post anesthesia discharge scoring system score of 9;Cognitive function assessment;feel sick; | — |
Countries
China
Contacts
Public ContactLu Yizhi
The First affiliated hospital of Guangxi Medical University
Outcome results
None listed