Osteoarthritis of the knee
Conditions
Interventions
Experimental group:Dexamethasone + Tranexamic Acid
Control Group: Tranexamic Acid
Sponsors
Xi'an Hong Hui Hospital
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients with definite diagnosis of knee osteoarthritis; 2. Aged 50 to 80 years; 3. It is planned to undergo unilateral knee resurfacing surgery; 4. Have signed the informed consent form to voluntarily participate in the researcher; 5. Patients who are not critically ill and may be life-threatening during diagnosis and treatment.
Exclusion criteria
Exclusion criteria: 1. Cardiovascular disease: severe cardiac insufficiency, abnormal mitral valve, tricuspid valve, arrhythmia, etc.; 2. Urinary system diseases: nephropathy; Stages 3 and 4; 3. Serious electrolyte abnormalities, severe anemia; 4. Mental illness; 5. Suffering from other serious systemic diseases that affect the conduct of the test or the observation indicators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tourniquet service time;The operation time;Intraoperative blood loss;Time spent in the hospital;Hemoglobin;D-dimer;C-reactive protein;Quadriceps muscle strength;Knee circumference;Fibrinogen;pain score;Creatine kinase;Lactate dehydrogenase ;B ultrasound of lower extremity vein; | — |
Countries
China
Contacts
Public ContactXu Peng
Xi'an Jiaotong University
Outcome results
None listed