Serum metabolomics of cognitive dysfunction after heart valve replacement under cardiopulmonary bypass

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100049439

Enrollment

Unknown

Registered

2021-08-02

Start date

2021-08-15

Completion date

Unknown

Last updated

2022-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cognitive dysfunction after heart valve replacement

Interventions

POCD group:None

unPOCD group:No

Eligibility

Sex/Gender

All

Age

45 Years to 64 Years

Inclusion criteria

Inclusion criteria: 1. Aged 45 to 64 years; 2, ASA I ~ III level; 3. Heart valve replacement was performed under CPB; 4. The informed consent has been signed.

Exclusion criteria

Exclusion criteria: 1. History of cerebrovascular, epilepsy and other central nervous system diseases, endocrine or metabolic disorders; 2. History of dementia, neurologic or mental illness due to various causes; 3. Language impairment, severe hearing or visual impairment, and a history of alcoholism; 4, currently using opioids, glucocorticoids or other hormones, sedatives.

Design outcomes

Primary

Measure	Time frame
Incidence of postoperative cognitive dysfunction;	—

Countries

China

Contacts

Public ContactWang Haiying

Zunyi Medical University

2371827590@qq.com.cn+86 18685268901

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026