Acute Pancreatitis
Conditions
Interventions
Experimental group:Transsigmoid fluid resuscitation
Control Group:routine intravenous fluid resuscitation
Sponsors
Rongxian People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Within 72 hours of onset; 2. Without fluid resuscitation (pre-hospital and out-of-hospital infusion volume <500ml/24h); 3. Moderately severe acute pancreatitis (MSAP) patients.
Exclusion criteria
Exclusion criteria: 1. Patients with confirmed or suspected malignant tumors, especially rectal cancer, colon cancer, gastric cancer, and genitourinary system tumors; 2. Immunosuppressed patients or have used or are using immunosuppressants within 30 days, or use glucocorticoids for more than 3 weeks within 60 days, or blood white blood cells <0.5x10^9/L, or platelets <25x10^9/L or more ; 3. Recurrent pancreatitis; 4. HGB<90g/L, chronic renal insufficiency, inflammatory bowel disease, colon polyps, peptic ulcer, etc., or those with contraindications to sigmoid colon tube placement; 5. Pregnant or lactating women; 6. Refuse to join the group or give up treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart rate;mean arterial pressure;Urine volume per hour;Inflow and outflow in 24 hours;Blood lactic acid;Hematocrit;urea nitrogen;brain natriuretic peptide;Intra-abdominal pressure;Modified Marshal scoring for organ dysfunction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of Acute Pancreatitis; | — |
Countries
China
Contacts
Public ContactWang Yu
Rongxian People's Hospital
Outcome results
None listed