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Effect of modified Mediterranean diet combined with alternate day fasting on intrahepatic fat content and hepatic fibrosis in patients with metabolic associated fatty liver disease

Effect of modified Mediterranean diet combined with alternate day fasting on intrahepatic fat content and hepatic fibrosis in patients with metabolic associated fatty liver disease

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100049420
Enrollment
Unknown
Registered
2021-08-02
Start date
2022-04-01
Completion date
Unknown
Last updated
2022-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

metabolic associated fatty liver disease

Interventions

Control group1:low-fat diet
Case group2:Modified Mediterranean diet group
Control group3:Alternate-day fasting
Experimental group:On the basis of group C, a modified Mediterranean diet was used

Sponsors

Hu'nan Provincial People' Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Adults aged 18 to 65 years; 2. B-ultrasound or CT or MRI confirmed the presence of fatty liver; 3. BMI>=23kg/m2, stable weight in the past three months (fluctuation <5kg); 4. Not participating in other research.

Exclusion criteria

Exclusion criteria: 1. Cardiovascular disease, uncontrolled hypertension, chronic inflammatory disease, chronic infection, cancer, weight loss, lipid-lowering or hypoglycemic drugs, and history of bariatric surgery; 2. Pregnant women and women planning to become pregnant or breastfeeding are also excluded.

Design outcomes

Primary

MeasureTime frame
Weight;height;Vital signs;the waist;hipline;—

Countries

China

Contacts

Public ContactCai Hua

Department of Gastroenterology, Hu'nan Provincial People' Hospital

965343605@qq.com+86 731 83928069

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026