Relationship between BCAAs metabolism and sarcopenia

Relationship between metabolic abnormalities of BCAAs and the mechanism of sarcopenia

Status

Active, not recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100049413

Enrollment

Unknown

Registered

2021-08-02

Start date

2021-07-31

Completion date

Unknown

Last updated

2022-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sarcopenia

Interventions

Case series:none

Eligibility

Sex/Gender

All

Age

60 Years to No maximum

Inclusion criteria

Inclusion criteria: Test group: 1. The diagnostic criteria for sarcopenia of the Asian Sarcopenia Working Group: (1) Muscle mass is less than two standard deviations from the standard value of muscle mass; (2) Grip strength: less than 26 kg for men and less than 18 kg for women (measured by the hand denominator used in the medical examination) or average pace of less than 0.8 m/s. 2. All selected from West China Hospital of Sichuan University; 3. Over 60 years old; 4. Sign the informed consent. Control group: 1. From West China Hospital of Sichuan University; 2. Over 60 years old; 3. Not suffering from sarcopenia; 4. No neurodegenerative diseases; 5. Patients without serious other systemic diseases.

Exclusion criteria

Exclusion criteria: 1. Suffering from neurodegenerative diseases, especially amyotrophic lateral sclerosis and Huntington's disease; 2. Patients with severe other systemic diseases.

Design outcomes

Primary

Measure	Time frame
branched chain amino acids;	—

Countries

China

Contacts

Public ContactLi Tao

West China Hospital of Sichuan University

scutaoli1981@scu.edu.cn+86 18980606762

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026