Effect of dexmedetomidine combined with esketamine on postoperative analgesia in accelerated rehabilitation surgery

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100049398

Enrollment

Unknown

Registered

2021-08-02

Start date

2021-08-15

Completion date

Unknown

Last updated

2022-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who require surgery and postoperative analgesia

Interventions

Group A:Dexmedetomidine combined with esketamine

Group B:Dexmedetomidine combined with sufentanil

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.General surgery, thoracic surgery, stomatology, ent, obstetrics and gynecology, orthopedics, urology, neurosurgery and other surgical patients who need surgical treatment; 2.Postoperative analgesia pump is needed.

Exclusion criteria

Exclusion criteria: 1.Patient refusal; 2.Serious cardiopulmonary insufficiency; 3.Unstable hemodynamics after operation; 4.Patients allergic to the drugs used in this study.

Design outcomes

Primary

Measure	Time frame
Interleukin-6 level;visual analogue scale;Ramsay sedation scores;Changes in cognitive function scores;15 item recovery quality score scale;Cortisol levels;Postoperative total pressing times and incidence of nausea and vomiting of patients;	—

Countries

China

Contacts

Public ContactTang Chaoliang

The First Affiliated Hospital of USTC

chaolt@ustc.edu.cn+86 13866777142

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026