Diabetic Nephropathy
Conditions
Interventions
Control group:Placebo
Sponsors
Changchun University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.At the same time, it meets the diagnostic criteria and syndrome differentiation criteria of Chinese medicine, and the diagnostic criteria of Western medicine for diabetic nephropathy; 2.The gender is not limited, and the aged 18 to 65 years; 3.HbA1c<=7%, for patients with severe complications such as recurrent hypoglycemia, severe microvascular or macrovascular complications, or patients who cannot meet the standard requirements after adequate treatment, HbA1c<=8%. 4.Control blood pressure below 130/80mmHg; 5.The patient knows and voluntarily participates in the trial study and signs the consent form, and has good compliance.
Exclusion criteria
Exclusion criteria: 1.Patients with mental illness who cannot cooperate with treatment and cannot follow the doctor's instructions to receive treatment on time; 2.Patients with recent acute complications and co-infection; 3.Women who are pregnant or breastfeeding or who are about to conceive; 4.People who are prone to allergies or are allergic to test drugs; 5.Patients who have undergone hemodialysis and kidney transplantation; 6.Patients with acute metabolic dysfunction complications such as diabetic ketoacidosis and hyperosmolar coma in the past month; 7.Suffer from other primary or secondary kidney diseases, or other diseases that can cause increased urine protein.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urine protein was quantified at 24h; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fasting blood-glucose;2h postprandial blood glucose;Glycosylated hemoglobin;Serum creatinine;Glomerular filtration rate;Serum metabolomics;Total cholesterol;Triglycerides;Low-density lipoprotein;High-density lipoprotein;Traditional Chinese medicine symptom scores; | — |
Countries
China
Contacts
Public ContactLiu Le
Changchun University of Chinese Medicine
Outcome results
None listed