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Study on the correlation of orthokeratology on the mucin expression of mRNA in tear fluid and meibomian gland of adolescents

Study on the correlation of orthokeratology on the mucin expression of mRNA in tear fluid and meibomian gland of adolescents

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100049384
Enrollment
Unknown
Registered
2021-08-01
Start date
2021-07-31
Completion date
Unknown
Last updated
2022-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dry eye

Interventions

case series:none

Sponsors

The Second Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
8 Years to 18 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria for myopia patients: 1.Aged 8 to 18 years, regardless of gender and race; 2.The near vision was normal, the far vision was = 1.0); 3.-0.5D <= diopter <= -6.00D, astigmatism <=0.75DC. Inclusion criteria of emmetropia group: 1.Aged 8 tod 18 years, regardless of gender and race; 2.No history of refractive error.

Exclusion criteria

Exclusion criteria: 1.Eyelid and skin inflammation, such as anterior blepharitis, atopic dermatitis, seborrheic dermatitis, rosacea, etc.; 2.Cicatricial lesions of eyelid and conjunctiva, such as trachoma, pemphigoid, chemical injury, thermal burn, radiation injury, etc.; 3.Eye medication history: drugs that affect tear secretion and tear film stability, such as artificial tears, corticosteroids, non steroidal anti-inflammatory drugs, etc.; 4.History of previous ophthalmic surgery, eye trauma and eye burn; 5.History of systemic diseases related to ocular surface diseases, such as rheumatoid arthritis, gout, rheumatic diseases, thyroid diseases and diabetes.

Design outcomes

Primary

MeasureTime frame
tear mucin mRNA;ocular surface indicators;

Countries

China

Contacts

Public ContactWang Jing

The Second Affiliated Hospital of Anhui Medical University

wangjing2980@163.com+86 15056967187

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 9, 2026