Acute liver failure
Conditions
Interventions
Combined with continuous hemofiltration dialysis and plasma exchange group:Continuous hemofiltration dialysis group and pasma exchange
Continuous hemofiltration dialysis, plasma exchange and dual plasma molecular adsorption system group:Continuous hemofiltration dialysis, plasma exchange and dual plasma molecular adsorption system
Sponsors
Shandong Provincial Hospital Affiliated to Shandong First Medical University
Eligibility
Sex/Gender
All
Age
No minimum to 18 Years
Inclusion criteria
Inclusion criteria: 1.Children diagnosed with acute liver failure; 2.Age ranges from 28 days after birth to 18 years of age.
Exclusion criteria
Exclusion criteria: 1.Severe cardiac, cerebral, or pulmonary diseases, or with active bleeding, or accompanied with disseminated intravascular coagulation; 2.Allergy to blood products or drugs used in blood purification (e.g. plasma, heparin, protamine, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 28 days survival rate;Days in pediatric intensive care unit;Total cost of admission to the pediatric intensive care unit; | — |
Secondary
| Measure | Time frame |
|---|---|
| Liver function;Coagulation function; | — |
Countries
China
Contacts
Public ContactJin Youpeng
Shandong Provincial Hospital Affiliated to Shandong First Medical University
Outcome results
None listed