Efficacy of dexmedetomidine versus midazolam for sedation and analgesia during burn dressing changes

Efficacy of dexmedetomidine versus midazolam when combined with butorphanol for sedation and analgesia during burn dressing changes

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100049325

Enrollment

Unknown

Registered

2021-07-30

Start date

2021-08-01

Completion date

Unknown

Last updated

2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burn injury

Interventions

Dexmedetomidine-butorphanol group:Use dexmedetomidine incombination with butorphanol before the dressing change

Midazolam-butorphanol group:Use midazolam incombination with butorphanol before the dressing change

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Burn patient who needs dressing change; 2.Burn area greater than 10% TBSA and less than 50% TBSA; 3.ASA score I-II; 4.Aged 20 to 60 years; 5.Cooperate with treatment.

Exclusion criteria

Exclusion criteria: 1.Allergy to drugs administered in this trial; 2.Sedative drug and analgesic drug abuse; 3.Complicated with severe organ dysfunction such as liver and kidney.

Design outcomes

Primary

Measure	Time frame
Sedation score;Pain score;	—

Secondary

Measure	Time frame
Mean arterial pressure;Heart rate;Respiratory rate;Oxygen saturation;	—

Countries

China

Contacts

Public ContactDing Xianchao

Affiliated Hospital of Jiangsu University

robertding3324@sina.com+86 13862446335

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 11, 2026