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Application value of multi-target stool FIT-DNA test (ColoClear) in patients with early colorectal cancer and precancerous lesions and their first-degree relatives: a prospective study

Application value of multi-target stool FIT-DNA test (ColoClear) in patients with early colorectal cancer and precancerous lesions and their first-degree relatives:a prospective study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100049309
Enrollment
Unknown
Registered
2021-07-29
Start date
2021-08-01
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

Gold Standard:Colonoscopy.
test&#32
(ColoClear).

Sponsors

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Patients with early colorectal cancer and precancerous lesions and their first-degree relatives who visited our center; 2.Voluntary signing of informed consent.

Exclusion criteria

Exclusion criteria: 1.Contraindications for colonoscopy and biopsy 2.Patients and their first-degree relatives have inherited diseases related to colorectal cancer, such as Lynch Syndrome, familial colorectal cancer type X Lynch-like syndrome, familial adenomatous polyposis (FAP), MUTYH-associated polyposis, Syndrome of hereditary pigmentation digestive polyposis, Juvenile Polyposis Syndrome (JPS), Serrated Polyposis Syndrome(SPS) etc.; Having other malignant tumors; 3.Pregnant and lactating women; 4.Participating in other clinical trials; 5.Other special conditions that the investigator considers inappropriate for participation in this clinical trial.

Design outcomes

Primary

MeasureTime frame
Sensitivity;Specificity;Positive predictive value;Negative predictive value;

Countries

China

Contacts

Public ContactLiu Mei

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

fliumei@126.com+86 18627714881

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026