Skip to content

Effect of functional exercise combined with anticoagulation therapy on early recovery of patients after total knee arthroplasty

Effect of functional exercise combined with anticoagulation therapy on early recovery of patients after total knee arthroplasty

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100049299
Enrollment
Unknown
Registered
2021-07-29
Start date
2021-08-01
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee joint disease

Interventions

Group A:Clinical multidisciplinary team (MDT) treatment
Group B:Orthopedic doctor guidance

Sponsors

Fuyang People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged >=18 years; 2. With indications for total knee arthroplasty, including: (1) knee osteoarthritis; (2) rheumatoid arthritis; (3) traumatic arthritis; (4) severe pain and/or dysfunction caused by lesions such as avascular necrosis or tumor; 3. The patient or legal representative has been informed of the nature of the study, understands the provisions in the protocol, and is able to ensure compliance.

Exclusion criteria

Exclusion criteria: 1. Venous thromboembolism has occurred before surgery (except for intramuscular venous thrombosis); 2. Use anticoagulants within 3 days before enrollment; 3. There is a high risk of bleeding, such as active gastrointestinal ulcers, congenital or acquired bleeding abnormalities (platelet count = 2 times during the study period; 5. Renal damage (creatinine clearance <= 20ml/min); 6. Accompanying severe blood disease or immune disease, or (and) receiving hormone therapy; 7. There are contraindications to antiplatelet, anticoagulant and thrombolytic drugs; 8. Active infection or neuroarthritis; 9. Flexor dysfunction, unable to actively bend the knee; 10. Asymptomatic knee stiffness; 11. There are serious medical and surgical underlying diseases before the operation, which makes the patient's walking severely restricted; 12. The patient participates in other clinical studies at the same time.

Design outcomes

Primary

MeasureTime frame
Venous thromboembolic events;

Countries

China

Contacts

Public ContactWang Hongliang

Fuyang People's Hospital

fywhl@sina.com+86 13956794773

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026